The lack of empirical data especially in the field of the volumetric overall mass transfer coefficient (K oc a) for design of pulsed packed columns with regular and irregular packing is one of the important scientific subjects in the front of researchers. Using of the correlations of other researchers about the other irregular packing that presented in the field of the K oc a and hydrodynamic parameters cause of high errors is not scientific and resulting spread of higher error and produce more errors and unactual results. Moreover in the field of regular packing have not been presented correlation for calculation of K oc a and hydrodynamic parameters and the more of K oc a correlation in literature is about of pulse sieve columns. The main objective of this study is to proposed the empirical correlations for calculation of the K oc a in these columns as a function of operating conditions (A f , Q c Q d ), packing characteristics ( and ) and physical properties of the liquid-liquid systems( ,,,, ). In this study two liquid-liquid chemical systems containing water/acetone/toluene (high interfacial tension) and water/acetone/butyl acetate (medium interfacial tension), two packing types containing (SMV regular packing and ceramic intalox saddle irregular packing) and also the axial mixing model have been used for prediction of the K oc a. No scientific report has been presented in the field of the K oc a for above packings until now. Also the effect of operating variables such a A f , Q c and Q d and also the effect of packing type and interfacial tension on continuous phase overall mass transfer coefficient have been studied. The range of change of above operating parameters is respectively (A f =1cm/s-3cm/s, Q c =8lit/hr-25lit/hr, Q d =10lit/hr-25lit/hr).