During the last 35 years membranes have evolved from a laboratory tool to industrial products with a wide variety of applications including desalination of sea and brackish water and treatment of industrial effluents. Today a large number of research works is done on ceramic membranes due to their inherent stability at hard operating conditions in comparison with polymeric membranes. In this research work an asymmetric ceramic membrane was manufactured by slip casting method using reactive ?-alumina. The experiments were designed by Taguchi method and the quantitative effect of important parameters such as sintering temperature, solid loading, and binder content on porosity and mean pore size of the membrane were investigated. In addition, the optimum level of dispersant in each solid loading was determined and the effect of different ball milling times on sintered body’s properties was probed. The cut off diameter of alumina powder was 4.012?m and Tiron was added to the suspension as a dispersant. Also PVA solution was used to prevent cracking during drying process. According to the obtained results ball milling had important effect on the slip cast body’s properties and the best milling time was found 3 hours. Taguchi analysis showed that sintering temperature is the main effective parameter on membrane porosity and this decreased largely with temperature increasing. The effects of sintering temperature and PVA content on membrane mean pore size were almost in the same order of magnitude and twice of this effect for solid loading. Very small contribution of error on the defined response proved that experiments were carried out in controlled condition.