packed liquid-liquid extraction column is a type of liquid-liquid extraction devices in which a soluble passed from the feed phase to the solvent phase. Due to the low space requirements and higher efficiency with respect to mixer-settler, this system can be used for the solvent extraction stage in copper mining. In this study, using computational fluid dynamics (CFD), packed columns simulate and the performance of these columns has been investigated in two stages. In the first phase, packed column hydrodynamics and in the second phase, mass transfer in these columns was investigated. A three-dimensional simulation, unstable and two-phase (liquid-liquid) was carried out. In this study Eulerian- Eulerian method is used. Continuity and momentum equations given the drag force using finite volume have been resolved. Both phases were considered turbulent and k-? turbulent flow model is used. The simulation results are in good agreement with the experimental data reported in the papers. After validation of the model, the effect of parameters such as the presence and size of the fillers, continuous and dispersed phases flow rate and the average diameter of the dispersed phase droplets on hydrodynamics and mass transfer of packed liquid-liquid extraction columns was investigated. The simulation results showed that the filler presence in liquid-liquid extraction columns causes increase efficiency and with reduce of the columns filler size, dispersed phase hold-up, therefore percent of the column extraction increases. According to the results, average diameter of the dispersed phase can influence the performance of the packed extraction column so that the increase in this parameter increases the hold-up and then turbulent occurs in the column. Also increasing the average diameter of dispersed phase droplets reduced the percentage of copper extraction in liquid-liquid extraction columns. The simulation results showed that an increase in the phases flow rate (In each case keep constant the other phase flow rate) increase dispersed phase hold-up and whatever continuous phase mass flow to the dispersed phase mass flow ratio increases, the dispersed phase extraction percentage decreases. By examining the results, a linear relationship to predict the amount of extraction in the packed liquid-liquid extraction column was obtained with 17.5 mm filler. Keywords : packed column, simulation, hydrodynamics, hold-up.