The treatment of edentulous patients with implant placement with great speed not only in terms of performance but also in terms of beauty is also in progress. But this knowledge is associated with problems such as defects of bone and connective tissue of the teeth caused by subsequent absence noted . During the past few decades tissue engineering approach guided tissue regeneration / bone and using natural and synthetic polymers combined with biodegradable ceramic nanoparticles in the membrane was developed blockers . The aim of the present study and characterization of fiber composite membrane layer of poly (glycerol Sbacat)–Polycaprolactone (beta-tricalcium phosphate / chitosan) using the electrospinning process. The pre-polymer poly (glycerol Sbacat) by condensation polymerization of monomers glycerol and Sebasic acid (molar ratio) were prepared and then evaluated using thermal infrared spectroscopy FTIR,DSC and evaluated . For bone conduction properties of nano-bio-ceramic membrane used of beta-tricalcium phosphate.In this regard nanoparticles by sol - gel synthesis and characterization of nanoparticles synthesized by X-ray diffraction (XRD) and test transmission electron microscopy (TEM) were studied. The polymer poly (glycerol Sbacat) alone. Therefore, the polymer PCL electrospun not due to favorable properties as second polymer was used. Then a solution of 15 percent by weight poly (glycerol Sbacat) / poly PCL with a ratio of 1: 1 in chloroform / ethanol ratio of 2: 8 was considered as a control sample. Since the membrane of two layers of nanoparticles beta-tricalcium phosphate ratio of 5 and 10 and 15% by weight of the composition of 15% poly (glycerol Sbasat) / poly caprlolactone as a layer GBR and of chitosan to about 20% by weight relative to the total weight polymers (glycerol Sbacat) / poly caprolactone as GTR layer. After optimization using electrospinning conditions and determine the ideal for each side of the membrane, the membrane mechanical testing, chemical - physical and biological received . The results suggest that chitosan combined chitosan / poly caprolactone/ poly (glycerol Sbacat) increased the hydrophilic fibers to the reduced size and increased porosity nm 274/7 nm was 85 percent, which aims to create Space correspond to prevent the entry of non functional cells . In addition, research has shown that chitosan can also be improved and healing. The presence of beta-tricalcium phosphate nanoparticles to 10% by weight of the composition of poly (glycerol Sbacat) / poly caprolactone improved mechanical strength up to about 1.32 ± 0.38 MPa was 209 ± 46% breaking strain . In addition to being hydrophilic and degradation rate increased porosity was 78%. Growth and cell reproduction in this case a significant increase compared to 15% of that due to the lack of aggregation of the nanoparticles in the polymer matrix . Key words: Nanofibers, Electrospining, GBR/GTR, Maxillofacial