The extreme consumption of Fossil fuels has caused concerns about energy crisis and environmental issues. Meanwhile, wind is known as an important renewable energy source converted mostly to the electricity. A wind turbine blade is considered the most critical part of the system and its fatigue life is of great significance in designing procedures. In this research, a glass-epoxy composite wind turbine of defined geometry and material is designed in Catia and simulated in ABAQUS under known loading. Blades were simulated with shell elements (S4R). Different parallel and perpendicular aerodynamic loads along the blade’s chord were analyzed and moved to the aerodynamic center calculated over different longitudinal stations and then every section was coupled to the aerodynamic center. Moreover, centrifugal load was taken into account in this analysis. centrifugal load caused 10% increase in tension and 10% decrease in compression in comparison with the results obtaioned by Spera method. Then, fatigue life was estimated by Spera empirical formula and Mandell method. This study aims at finding the biggest possible dimensions for the blade taking design and strength considerations into account. In this regard, the blade was redesigned with 20% increase in dimensions keeping the load per area constant and two designs were presented for composite lay-up and strengthening elements (spar and web) assuming a lifetime of 20 years. The results showed improvement in fatigue safety factor under tension and compression. To verify the accuracy of implemented lay-up in simulation, several Coupon of turbine material were fabricated. Elastic properties of coupons were measured using standard tests such as tension. Torsion, pure and anticlastic bending tests were also carried out to verify the corresponding simulations. Keywords : Turbine Blade, Wind Energy, Glass-Epoxy Composite, Fatigue Life, Coupon Test, Anticlastic Bending