In recent years, the application of the Additive Manufacturing (AM) has been increased due to the construction of complex components at one stage and the reduction of the cost of manufacturing in various industries, such as medicine, aerospace, and automotive. In this study, the effect of post-processing parameters of fabricated 316L stainless steel Binder Jet Printing (BJP) on the microstructural and mechanical properties including compressive strength, the percentage of shrinkage, relative density percentage, porosity size, and percentage of open and closed porosity, and the neck size ratio were investigated. In the tests, it was found that the parameters of the sintering temperature, the holding time and heat rate were effective on the microstructural and mechanical properties of the specimen. Sintering temperature and holding time were effective in microstructural and mechanical properties because their values have the greatest impact on the neck size ratio. It was also shown that the neck size ratio has a direct correlation with the microstructural and mechanical properties, while the heating rate has the minimum effect on the properties. According to the obtained results, it is possible to select the proper parameters of the post-processing based on the application of the 316L stainless steel produce by BJP to reach the desired properties. Keywords: Binder Jet, Sintering Parameters Optimization, SS316L, Micro-structural and Mechanical Properties