Our research consists of experimental and theoretical studies. In experimental studies, mesoporous nano-aluminas were prepared using aluminium isopropoxide, vitamin C and water. The structure of alumina were investigated. Then these products were deployed as catalyst in dehydration of 2- octanol, and products distribution were investigated. The role protection of hydroxyl groups on stability of vitamin C were investigated by comparison of degradation of VC and its derivatives. In theoretical studies, the adsorption energies (E ads ) and relative stabilities of selected conformers of the most stable tautomer of L-ascorbic acid (vitamin C) on the dehydroxylated ?-alumina (1 0 0) surface were calculated in gas phase and solvent (water) using DFT method. In the other theoretical research, the ability of cyclic peptides composed of 4, 5, 6, 7, 8 and 9 phenylalanine building blocks as the chiral discriminating agents for the separation of phenylalanine enantiomers (D and L) has been investigated in gas phase and water. The calculations have been performed using DFT. The interaction energy ( E int ) of each cyclic peptides with the enantiomers of phenylalanine have been calculated. The natural bonding orbital (NBO) analysis was also performed to determine the hydrogen bonds between the enantiomers and cyclic peptides and their strength.