In this project, at first a series of amides were prepared by the reaction of the aromatic carboxylic acids with both aromatic, and aliphatic isocyanates in 1,3-diallylimidazolium bromide as a solvent. This reaction compared with the other reaction using conventional solvents such as N -methyl pyrrolidone (NMP), N,N ' -dimethyl formamide (DMF), and toluene. It revealed that by using ionic liquid as a solvent, the better results in terms of yield, and selectivity are obtained. By using this reaction, the polymerization of terephthalic acid with either aromatic, and aliphatic diisocyanates are carried out both in NMP, and molten tetrabutylammonium bromide (TBAB), then the obtaining polyamides (PA)s are compared with each other in terms of inherent viscosity, yield, thermal stability, and their colours. On the next project starting from L-phenylalanine, phthalic anhydride, and 5-aminoisophthalic acid, the novel optically active amidic diacid, (2s)-5-(3-phenyl-2-phthalimidylpropanoylamino)isophthalic acid are prepared in three steps. The chemical structure of this monomer was confirmed by spectroscopic techniques like FT-IR, 1 H-NMR and 13 C-NMR, specific rotation, and elemental analysis, then the polyamidation of this monomer with aromatic diamines are performed by using NMP/triphenyl phosphate (TPP)/calcium chloride (CaCl 2 )/Py as a medium via direct polycondensation reaction. The inherent viscosities of these polymers are in the range of 0.28-0.49 dL/g Also they had good solubilties. The chemical structure of these polymers are also characterized by FT-IR, 1 H-NMR, and elemental analysis. At the end the similar polyamidation reactions are were in the presence of TPP, and 1,3-dipropylimidazolium bromide, and the new optically acive PAs are obtained with inherent viscosity in the range of 0.30-0.52 dL/g. It showed the better solubilities, yields, and thermal stabilities than the previous method.