Asymmetric synthesis is one of way to synthesis of drugs and biologically compounds. Different drugs have been synthesized with this method, for example Thalidomide was synthesized for treatment of morning seek phenomenon. This compound was synthesized in racemic mixture has a bad side effect in Childs that their mothers used this drug. This drug has two enantiomers, one of them has drug effect and the other have side effect. Hence, the importances of asymmetric synthesis are being characterized.In this thesis according to asymmetric synthesis, we were synthesized some optically active compound. at first project by using of L- alanine and [BMIM] Br catalytic system, prepare an chiral reaction medium. We could synthesis secondary alcohols by reduction of prochiral ketones in our reaction medium in presence of NaBH 4 with low to moderate enantiomeric excess. Amino acids are not soluble in most organic solvents, but soluble in ionic liquids. We were used dissolved amino acid in ionic liquid and preparation a homogeneous catalytic medium. Amino acid in this system has chiral inducement rule. In the second and third projects by changing synthesis method, we were trying to preparation of a catalytic solid state containing optical active polymers with oxidative effect. We could synthesize two types of these coordination polymers. At first we synthesized a complex of copper (II). This complex in presence of H 2 O 2 converted sulfides to sulfoxides. Then some chiral di acide imide prepared by combination of some dianhydride and amino acids. At the end these two organic and inorganic monomers have been polymerized in catalytic system of pyridine and thionyl chloride. These poly (ester- Imide- Salen)s are able to oxidation of some organic compounds such as sulfides.
