A combination of environmental interest and chemist curiosity in regard to natural phenomena, lead us to biomimetic catalysts such as immobilized metalloporphyrins, as cytochrome P-450 models, and their potential for substrate oxidation. Metalloporphyrins are well known for their ability to carry out a wide range of oxidation reactions in homogeneous systems. The current trend in the research into catalysis by these compounds is to anchor the catalytically active metalloporphyrin species on a solid support as it is expected that immobilization will facilitate the catalyst recovery and reuse. The central objective of this research is to carry out oxidation reaction of cumene and produce acetophenone and ?-cumyl alcohol as the main products, using heterogeneous catalyst. Thus, this projects aims to design a heterogeneous catalyst based on the immobilization of porphyrin on silica gel. In order to do this, the porphyrin containing steric functional group, entitled 5,10,15,20-tetrakis (4-methoxycarbonyl phenyl) porphyrin , was synthesized and immobilized using amidation reaction on modified silica gel (containing amino functional group). Ultimately immobilized porphyrin was transformed into M(III) complex that M was Mn, Fe and Co.Different techniques such as UV-Vis, FT-IR, ICP and TEM were used for characterization of the catalysts called SF-ATPS-M(III)TMCPP. Eventually, these catalysts were used for oxidation of cumene .The products were acaetophenone and ?-cumyl alcohol. We optimized, some various operation parameters such as temperature, solvent and oxidant to raise the conversion percentage and selectivity of acetophenone and ?-cumyl alcohol as the main products. The conversion of cumene and selectivity to acatophenone were maximum under temperature 80 ?C and acetonitrile as solvent. We have selected t-butylhydroproxide (80%) [TBH 80%] as the best oxidant in the oxidation reaction of cumene . In order to study the catalyst deactivation of the cumene oxidation , we carried out this reaction several times with modified SF-ATPS-Mn(III)TMCPP. Our data showed that SF-ATPA-Mn(III)TMCPP was the active, stable and selective catalyst for oxidation of cumene. Finally, these catalysts were used for oxidation of toluene, o-xylene and p-xylene . It indicated .