Among various types of alcohols, 2-propanol is one of the most promising candidates for direct alcohol fuel cells (DAFCs). 2-Propanol is less toxic than methanol, it is less prone to crossover to the cathode, and it is not poison to the cathode like the methanol. In this project, a porous anode electrode was made based on the Pt-free Hypermec TM ( Fe-Co-Ni/C) nanocatalysts for evaluation of 2-propanol electrooxidation in alkaline media. Performances of the mentioned electrode and conventional palladium anode electrode in 2-propanol electrooxidation reaction were compared. The electrochemical behaviors of these electrodes were investigated by cyclic voltammetry and chronoamperometry techniques. Also, Scanning electron microscopy (SEM) was employed to study the structure of catalyst layer. The chronoamperometry results showed clearly that the Pt-free Hypermec TM is a better catalyst for 2-propanol oxidation reaction than the Pd/C (10% wt) , drop of the current for the Pd/C (10% wt) electrocatalyst was almost 43% more than the Pt-free Hypermec TM electrocatalyst. The maximum current density value obtained for the Pt-free Hypermec TM was 15 µA µg -1 metal and for Pd/C (10% wt) was 11.5 µA µg -1 metal . therefore, the Pt-free Hypermec TM electrocatalyst had a higher catalytic activity than Pd/C (10% wt) electrocatalyst.. The results of D2PFC tests showed a maximum power density of 8.5 mW cm ?2 with Pt-free Hypermec TM anode catalyst and 9 mW cm ?2 with the Pd/C (10% wt) anode catalyst at 25 ? C. results obtained for D2PFC were consistent to the chronoamperometry and cyclic voltammetry measurements.