The main purpose of this research work is synthesis and application of some mono and dicarboxylate of metals group II and X of periodic element such as Pb, Ca, Cd, Zn and Ba as thermal stabilizers in polyvinyl chloride (plastisol) prepared by emulsion process. For this purpose, these compounds were synthesized by reaction of a monocarboxylic acid such as stearic acid and a dicarboxylic acid as adipic acid with compounds such as oxides, chlorides, or carbonates of the mentioned metals in obtimized conditions. Then different amounts of the synthesized carboxylates were added to the PVC plastisols and heated them in a curing oven. The film samples were tested by different methods such as FT-IR, TGA, measurement of HCl released during processing, ESM and tensile tests. All the obtained results confirmed thermal stability and synergistic effects of the thermal stabilizers in the polymer.