In this thesis, a 4-nitrofenyl cyanamide high purity ligand was first prepared. Then the Mn (II), Co (II), Cu (II) and Ni (II) complexes were synthesized by phenyl cyanamide ligand and rosuvastatin ligand. Phenyl cyanamide ligands have a strong peculiarity of character, hence the ability to cordulate with the central metal from the two ends of nitrogen and amine. This strong peculiarity is due to the presence of three atoms in the NCN group, which creates a continuous ? system within the molecule. Another ligand that was used was rosuvastatin, a group of statins that, by inhibiting the hydroxyethyl-glutaryl-coenzyme reductase enzyme, reduced the level of cholesterol in the blood. The complexes of Mn (II), Co (II), Cu (II) and Ni (II) were identified with two rosuvastatin and 4-nitrofenyl cyanamide by IR and UV-vis methods. The anticancer effects of the compounds on the MCF7 and hela cancer cell line were investigated using MTT (methylthiazole tetrazolium) method. Also, the antibacterial effect of complexes on Staphylococcus aureus and Escherichia coli bacteria was studied.