Mesoporous silica nanocarriers are used in new drug delivery systems because of their special features, including high specific area, good biocompatibility, high mechanical and thermal resistance, large pore volume for loading large amount of drug molecules, and easy surface functionalization. In this thesis, pH-sensitive, folate-targeted silica mesoporous nanocarriers were synthesized. The FT-IR, XRD, FE-SEM, TEM, Zeta-potential and DLS data confirmed the successful synthesis of nanocarriers. Then, carminic acid, the drug extracted from cochineal, due to its similarity to anthrasycline drugs like doxorubicine was loaded on synthesized nanocarriers. The optimum amount of drug loaded in 1 mg of nanocarriers was calculated with comparing, loading capacity and loading efficiency for various ratio of drug to nanocarriers. The invitro drug release manner was studied by UV-Vis spectroscopy. The results proved that the cumulative drug release inside the tumor acidic pH is more than this amount in a biological environment. The MTT assay was used to visualize the specific targeting ability and anticancer activity of the synthesized compounds against the HeLa and K-562 cell lines.