A new method based on corona discharge ion mobility spectrometry (CD-IMS) was developed for analysis of biogenic amines including, spermine and spermidine. n-Nonylamine was used as the reagent gas to control the ionization processes and enhance the selectivity. It was also realized that ion mobility spectrum of n-Nonylamine was changed with its concentration. Furthermore, a sample injection port of a gas chromatograph was modified and used as the sample introduction system for the CD-IMS. The detection limits and dynamic ranges of the calibration plots for Spermine and Spermidine were about 0.2 µg/mL and 2 orders of magnitude, respectively. The wide dynamic range originates from the high current of the corona discharge and this method does not need to derivatized the compounds. The results revealed high capability of the CD-IMS for analysis of the biogenic amines. The potential of CD-IMS for simultaneous analysis of Tetramethrin and Bifenthrin and mixtures of the compounds was investigated. In this way a three dimenthional data was obtained for the samples. The data was modeled by using the second order calibration method of Tucker 3. The results revealed the capability of the method.
