A newly fluorescent probe for the recognition and detection of bisphenol A (BPA) has been created on molecularly imprinted polymers (MIPs) shell on chromium (III) oxide nanoparticles (Cr 2 O 3 NPs), by taking advantages of the high selectivity of MIPs and the strong fluorescence property of Cr 2 O 3 NPs. At the first step of this work, 3-mecaptopropionic acid capped Cr 2 O 3 NPs (3-MPA capped- Cr 2 O 3 NPs) were prepared using micro emulsion method. Then MIPs-coated Cr 2 O 3 NPswere formed by anchoring MIP layer on the surface of Cr 2 O 3 NPs by one-pot precipitation polymerization with surface imprinting. In this step, methacrylic acid (MAA), ethylene glycol dimethacrylate (EGDMA) and 2,2¢-azobis (2-methyl propionitril) (AIBN) were applied as the functional monomer, the cross linker and the initiator, respectively. In the presence of imprinting template BPA, a hydrogen bonding could be formed between BPA and the carboxylic acid groups on the surface of the Cr 2 O 3 NPs, and the photoluminescent energy of Cr 2 O 3 NPswould be transferred to the complex, and thereby result in the fluorescence quenching of Cr 2 O 3 NPs. face of the Cr 2 O 3 NPs, and thereby result in the fluorescence quenching of Cr 2 O 3 NPs. The fluorescence intensity of composite decreased in 15 min, and the dynamic range of the optical sensor was 0.04-4.4 ?mol.L -1 BPA and the detection limit could reach 0.015 ?mol.L -1 . The relative standard deviation of 2.2% and 1.3% for 0.14 and 3.1 BPA (n=3) were observed. This composite material has a high selectivity with an imprinting factor of 6.26. The present study provides a new, simple and cheap strategy to fabricate inorganic-organic MIP-coated Cr 2 O 3 NPswith monitoring of BPA in aqueous media and is desirable for chemical probe application.