Although several methods have been proposed for regeneration of saline soils, but desalination is the best method. The most disadvantages of desalination are that they are costly and energy intensive. To investigate the ability of five adsorbents (peat, activated carbon, zeolite, anionic resin and cationic resin) in single and combined forms, to remove salinity ions from aqueous solutions, 15 treatments were prepared for a batch experiment in micro and nano conditions, using saline drainage waters of 5.1, 10.1 and 20.8 dS/m, respectively. The column test was conducted using the four adsorbents which had the best results in batch experiment. Study results showed that in salinity of 5.1 dS/m anionic-cationic resin, in salinity of 10.1 dS/m cationic resin and in salinity of 20.8 dS/m, peat, peat-cationic resin and activated carbon-cationic resin had the most adsorption of salinity ions. Nano process caused more salinity adsorption as compared to micro conditions, but the salinity reduction by nano particles was negligible as compared to micro particles. Nano process in salinities of 5.1 and 10.1 dS/m was more effective than in salinity of 20.8 dS/m.