Potato is one of the main agricultural crops in Iran and world. In all over the world and especially in Iran , the main limiting factor for crop production is water. Deficit irrigation is a suitable method for saving water, reducing costs and increasing income. To study the effects of different furrow irrigation methods on yield and water use efficiency (WUE) of potato, a field experiment was conducted during summer 2007 in Isfahan Agricultural and Natural Resources Research Center (Rezveh Station) using completely randomized blocks design with three replications. Irrigation treatments were irrigation after 75, 100 and 120% cumulative evaporation from class A pan. The irrigation methods were ordinary furrow irrigation, PRD, every other furrow, every other furrow up to the middle of season, every other furrow from the middle of season and furrow with two planting rows on the top of the furrows. The results showed that the application efficiency of PRD (93.8%) is higher than the ordinary furrow irrigation. The effect of irrigation method on potato yield was significant (p 0.01). The lowest yield (16.13 t/ha) was belonged to every other furrow up to the end of season and the highest yield (24.47 t/ha) was belonged to every other furrow up to the middle of season. The effect of irrigation water amount on yield was significant (p 0.01). The highest yield (25.82 t/ha) and the lowest yield (13.84 t/ha) were belonged to the irrigation treatments of 120% and 75%, respectively. The effect of irrigation method on WUE was significant (p 0.01). The highest WUE were belonged to every other furrow up to the middle of season (5.33 kg/m 3 ) and PRD (5.24 kg/m 3 ) and the lowest WUE was belonged to furrow irrigation with two planting rows (3.78 kg/m 3 ). The effect of irrigation amount on WUE was significant (p 0.01). The highest (4.68 kg/m 3 ) and the lowest (3.82 kg/m 3 ) WUE were belonged to the 100% and 75% irrigation treatments, respectively. The effect of irrigation method on percentage of tubers greater than 55 mm was significant (p 0.01). The highest amount of tubers larger than 55 mm (30.44%) and the lowest amount (16.38%) were belonged to every other furrow irrigation up to the middle of season and furrow irrigation with two planting rows, respectively. As the irrigation water increased the percentage of tubers larger than 55 mm increased.