Secure demands and food security and high population growth forced the governments and researchers attention toward sustainable agriculture. Land-use change is one of the human strategies to use new soil resources for more productivity. Depending on climate and environmental condition, land-use changemay have positive or negative effects on soil quality. Carbon dioxide emission to environment can change global climate. Soils have a great role on global carbon cycle. Land-use is one of the factors affectingsoil carbon. Therefore, measuring soil quality for evaluating effect of crop management on soil diversity, yield capacity, stability and environmental quality is essential. This study was done for evaluating effect of land-use change and depth on soil quality indices in Lordegan, ChaharmahalvaBakhtiari Province, Iran. Soil samples were taken from seven land-use systems in three replicate (105 samples): forest withlow grazing, forest with medium grazing, pasture with medium grazing, pasture with high grazing, dry land farming, fallow and alfalfa at five depths: 0-15, 15-30, 30-45, 45-60 and 60-75 cm. Particle size distribution, bulk density (BD), relative, bulk density (RBD), equivalent calcium carbonate (CaCO 3 ), electric conductivity, soil reaction (pH), organic matter (OM), total nitrogen (N) and soil respiration were all measured in the soil samples. Analysis of variance (p 0.05) showed that interaction effect between depth and land-use have significant effect on BD to 45cm so that pasture surface soil with high grazing had maximum BD (1.5 Mg m -3 ) and forest with low grazing had minimum BD (1.2 Mg m -3 ). Surface OM was the highest in forest with low grazing (5.1%) and the lowest in dry land farming, fallow, pastures with medium and high grazing (1.67, 1.72, 1.67 and 1.78% respectively). In the second depth, OM was the lowest in pasture with medium grazing and no significant differences in other land-uses. Effect of land-use on OM have no significant effects in the other depths. Interaction effect between land-use and depth wasn’t significant for the other parameters. Comparison major effects of land-use showed that soil respiration was highest in dry land farming (2894 mg kg -1 in week) and lowest in pasture with high grazing and forest with medium grazing (520, 663 mg kg -1 in week). The amount of N was the maximum in forest with low grazing and alfalfa and minimum in pasture with medium grazing. Result of this study showed that OM%, N% and soil respiration decreases with increase depth. Correlation analysis showed that often measured soil parameter in this study (except respiration and CaCO 3 ) had significant correlation with OM. This shows that OM controls the property for soil quality in these soils. The correlation is not significant for OM and soil respiration resembles that in soil respiration depends on other soil parameters rather than the OM. Keywords : Land-use change, Soil quality, Lordegan, Soil respiration, Soil organic matter