Moths of the family Sesiidae are among the most destructive pests of fruitful and non-fruitful trees in all over the world. In this study, several issues including identification of damage-causing species, the percentage and intensity of infestation on various trees under natural conditions, biology and population variations of the dominant species on plane trees, effectiveness of pheromone traps and the effects of some chemical control procedures were studied in Isfahan landscapes. Species identification was done by sequencing the cytochrome oxidase I (COI) region. Brownish droppings as active larval infestations and blackish one as old infestations as well as total number of pupal exuviae were used to determine the percentage and intensity of infestation on various trees under natural conditions. The biology of pest was assessed by weekly sampling or twice a week at critical stages in 2012 and 2013at two Isfahan municipality regions. Sampling was done by skin removal and counting the number of larvae and pupae. Some reproductive parameters were determined in the laboratory conditions (26 ?C and 40 5 % humidity) by rearing collected pupa from plane trees. The effectiveness of three pheromone products in the monitoring of dominant population was assessed in three Isfahan municipality regions. The effects of two chemical control procedures was also determined, including trunk spraying with imidacloprid, deltamethrin and chlorpyrifos and trunk injection with imidacloprid, oxydemeton methyl and azadirachtin in two municipality regions. The results demonstrated that damaging species in Isfahan landscapes are belonged to Synanthedon caucasica (Gorbunov) causing damage to plane and elm trees and Sesia pimplaeformis (Oberthür) causing-damage to willow, poplar and aspen trees. The infestation percentage results showed that 53.8 Platanus orientalis , 64.4 Ulmus carpinifolia , 65.6 of Ulmus carpinifolia var umbraculifera , 45.2 Populus alba , 52.6 Salix alba and 53.2 of total host trees were infested by these pests. The results of field studies on the biology of S. caucasica showed that this species is univoltine and overwinter as late instar larvae. Adults begin to emerge in mid-April and emerging continues until August. The peak of the adult population happened at the third decade of May and larval population’s peak happened in the third decade of July. Traps baited with of S. myopaeformis pheromone (Agrisense Company) were more effective than traps baited with S . myopaeformis pheromone (Trifolia-M Company) or S . tipuliformis pheromone (Chem-Tica International S.A. Company) for trapping of S. caucasica adults. Based on the alive larval populations under trunk bark four months after treatment, the results of chemical control demonstrated that spraying with chlorpyrifos was more effective than imidacloprid and deltamethrin spraying, while trunk injection with azadirachtin and oxydemeton methyl were more effective than imidacloprid injection. Although these findings are useful in the management of the pest, more research should be carried out on the identification and synthesis of the pest pheromone and evaluation of other pest control tactics.