Due to the lack of water in arid and semi-arid, water reuse is essential. There are various water desalination technologies including reverse osmosis, filtration and electrodialysis. Use of phytoremediation for desalination of saline water is considered as a low-cost and environmentally friendly method. In this study, the ability of three plants ( Cynodon dactylon L . , Portulaca oleracea L. and Kochia scoparia L . ) was investigated to reduce water salinity. For this purpose, seedlings of the plants were grown in a hydroponic system having different salinity levels (0, 4, 6, 8, 10 and 12 dS/m) for 60 days in the research greenhouse of Department of Natural Resources, Isfahan University of Technology. Water electrical conductivity (EC) was measured every two days. Removal of water salinity, concentration of sodium accumulated in plant tissue as well as plant dry weight (root, stem and leaves) were measured after growing period. Removal of water salinity reduced by the plants with increasing the salinity level where the maximum efficiency at EC of 4 dS/m by Cynodon dactylon, Portulaca oleracea and Kochia scoparia was 82, 85 and 90 percent, respectively. The ability of Kochia scoparia in sodium accumulation was more than the other plants because of more tolerance in the growth media and higher biomass production. Sodium accumulation in shoot and root of plants increased until EC of 8 dS/m and then decreased. The highest sodium accumulation was in root, leaf and stem; stem, leaf and root; and leaf, roots and stem of Cynodon dactylon, Portulaca oleracea and Kochia scoparia, respectively. Overall, the phytoremediatiom mechanism of the studied plants could be salt accumulation in shoots and roots. Keywords : Desalination, Phytoremediation, Cynodon dactylon, Portulaca oleracea , Kochia scoparia , Sodium accumulation