Land use / land cover has a direct impact on the quantity and quality of groundwater and surface water. Land use change in the Segzian plain has created numerous ecological and environmental problems for surface and underground waters. Land use and its spatial pattern and its impact on the quantity and quality of surface water and underground waters are essential for achieving better insight into management strategies. Remote sensing is used as a valuable method for monitoring, diagnosis and identification, especially in the process of preparing land use maps in different parts of the world scientifically. Monitoring changes is an important process in the application of remote sensing. Comparison after classification is one of the most practical methods widely used for monitoring land use change and land cover. In this study, the effect of land use change / land cover on several parameters and quality of surface water and groundwater in Segzian plain was investigated. Landsat TM images of the years 1993, 2000, and 2009, Landsat ETM + satellite in 2006 and the OLI satellite for the year 1395 were used to provide a map of land use and land cover and to investigate the trend of its changes. To do this research, all of the images were first exposed after the required pre-processing, using the analyzes and indicators. Finally, the hybrid classification was used to categorize the images. After classification, user's maps and land cover in 10 categories of agricultural land, garden, rangeland, Bayer, aquatic areas, rocky outcrops, sand dunes, vegetation around the lagoon and saltpipes with accuracy Acceptable. Then, the comparison method after classification in the LCM model was used to detect the changes that occurred during this time frame. After revealing the changes, in order to investigate the effect of the user's experiences on the quantity and quality of surface water of the Ministry of Waters, to calculate the Groundwater Quality Index (IRWQIGC), Surface Water Quality Index (IRWQSC), Agricultural Water Quality Index (IWQI), and Indicator World Health (WHOWQI). To calculate water quantity, wellness and discharge data were used. Monthly statistics of physical and chemical parameters, groundwater level, Dubai Charging Station and Varzaneh rain-storm stations, agricultural production statistics were collected from Isfahan Jihad-Agricultural Organization and Amar precipitation from the country's meteorological site during the 29-year statistical period (1966-1363). The results of this study showed that during the period of 1962-1372 and 1379-1379, the earthquake level and the amount of water entering were increased, and part of the use of pasture, Bayer and Dandelion for use Agriculture has changed and the area of agricultural land and agricultural production has increased. IRWQIGC, IWQI and WHOWQ indices in these time intervals are classified in the relatively poor class due to the classification of groundwater quality indexes in the middle class and IRWQISC quality index, which can increase rainfall in this interval It's time. In terrible conditions, the level of groundwater level and the amount of intake have increased, which has reduced the salinity and agricultural pesticides, therefore, water quality indicators are placed in a better (moderate) category than drought periods. In the periods between 1379-1372 and 1388-1385, when the drought occurred, groundwater level, water intake and rainfall decreased, and a part of agricultural land was converted to drought, habitat, bayer and pasture land use. The results of quality indices, IRWQIGC, IWQI and WHOWQI in these time intervals have been classified in the bad class due to the classification of groundwater quality indices in bad and inappropriate class and IRWQISC quality index. In general, the time trends of water quality indicators show a decline in the quality and quantity of surface water and underground water. Any surface runoff pollution in the upstream (Paul Chowm) has a lot of downside effects (Varzaneh). The level of agricultural production, the level of groundwater level, the rate of water flow, and the quality of groundwater are effective. It seems that if the necessary measures to control the exploitation of surface water and underground water and the use of fertilizer in agriculture and effective management measures in this sub-basin, the quantity and quality of surface water and groundwater in the plain As a result, problems arise from the point of view of drinking water and agriculture, and ultimately, the economic and social situation of the basin may be at stake.