Zefreh Cu-Mo prospect is located in 75kmortheast ofIsfahan and20 kmorth ofthe Zefreh village.It is located in the main porphyry Cu belt of Iran (Orumiye-Dokhtarvolcanic arc) and may have high potentialfor furtherexploration. Therefore, identification of controls on mineralization are required. In theresent research,the studywaoriginallydesignedto proceAster satellite imagery data to map hydrothermal alterations.Afterensuring theresence ofalteratioystems, geological, geochemicalandgeophysicaltudies was performed to map other mineralizing controls at the prospect. Aster images were processedusingfalse-colorcomposite (RGB), band ratio, principal components analysi(PCA)andleast squareregressio(LS-Fit) methods and then argillic,hyllic propylitic alteration zones as well as irooxides were identified. In order to prepare 1:5000 geological map, Aster VNIR RGB images were used as base map, followed by field checking and taking fifteerock samplefromoutcrops for petrographic and mineralogical studies. Microscopic and petrographyiections of the samples showed that thetudy areais mostly covered by daciteorphyry, diorite,granodioriteorphyry, andesitic lava and hydrothermaltuff breccias. Study of polished/thin sections, under the normal microscope, showed mineraluch yrite, sericite,ka olinite, hematite, goethite, magnetite,tourmaline, biotite and hornblende. Five main types of alterations such as phyllic,otassic,argillic,ropylitic, andilica were confirmed in this study. A systemic geochemical survey applied in the area by taking 235 chip samples within interval ranges of 50*50 in the central part of the prospect and 150*150 in surrounding part. Sample were analyzed at Zarazma laboratory by ICP method for 44 elements. asic statistical analyses and anomaly separation methods such as .N,, gap statistics and fractal were used in this research. The model,utilizedifractal method,waconcentration area. Then multivariatetudies of clusterand factorial analysewere erformed to prepare different geochemical anomaly maps.Two IP/RS geophysical profiles were applied at the phyllic alteration and breccia zones using pole–dipole electrode method. The IP/RS signatures confirmed the presence of a sulfide zone at the depth of 40 meters. On the basis of integrated analyses ofremotely-sensed data,urfacegeochemicalanomalies, IP/RS geophysical signatureand surface geologicalevidences, Mineralization at Zefreh prospect were considered as Cu-Mo porphyry type and the location, dip and depth of 4 borehole were proposed for test drilling.