Portland cement is known as the most widely used building material and also as the second most consumed material after water. The huge volume of production and use of this material comes with many side costs such as significant energy consumption and, high emissions of greenhouse gases. Therefore, replacing Portland cement with new binders with lower environmental effects and better performance such as alkali-activated binders is necessary. In this study, experiments were performed by replacing all Portland cement with alkali-activated slag in order to eliminate the environmental effects of Portland cement production . Alkali-activated materials are usually formed in two-parts from a combination of an alkali solution and an aluminosilicate solid. Due to the high alkalinity, corrosion, and of course the viscosity of these alkaline solutions, storage, and traortation of them and the process of combining with solids for constructions in large scales becomes difficult. Therefore, the first step in the direction of mass consumption of these materials in the construction industry is the development of one-part alkali-activated materials from the combination of aluminosilicate materials and solid activators as an alternative method. In this method, similar to Portland cement, chemical reactions begin only by adding water to this solid compound. It should be noted that the rate of drying shrinkage in alkali-activated slag concretes has been reported more than ordinary concretes up to several times. Miscalculating the shrinkage in the design of concrete members and structures leads to non-structural cracking or warping of the structure, displays the importance of studying, and recognizing this phenomenon in alkali-activated slag concretes. In this research, the drying shrinkage of one-part alkali-activated slag concrete and the factors affecting it have been investigated analytically and experimentally. In addition to the drying shrinkage test of the produced mixing proportions, a 28-days compressive strength test, slump test, and density test were also performed. In the first stage of the research, experiments were performed with 50%, 52% and, 54% the water to the binder. The compressive strength had a decreasing trend and the drying shrinkage has an increasing trend by increasing the water amount. In the second stage, the effect of zero, 5%, 10% and, 15% of microsilica has been investigated. By increasing the microsilica from zero to 5%, an increase in compressive strength was observed. Also, in most of the tested cases, by increasing the microsilica from 5% to 10%, the compressive strength slightly decreased, which finally, by increasing the microsilica to 15%, the compressive strength sharply decreased. Also, by increasing the microsilica, the drying shrinkage was decreased. At the third stage of the research, the effect of alkali activator was also investigated with 18% as group one (G1) and 20% as group two (G2). The drying shrinkage for mixing proportions for group one was calculated close or a little more than the mixing proportions for the group two except in mixing proportions with 15% microsilica. The fourth step was to study the curing method, which in all the mixing proportions except for 15% microsilica, the compressive strength of the specimens in plastic bags was approximately equal to or slightly less than the compressive strength of specimens cured underwater. Also, the drying shrinkage of wet cured specimens was less than the specimens covered by plastic. Finally, by using three-quarters of the experimental data, an analytical model was presented to predict the drying shrinkage of one-part alkali-activated slag concrete during the time. By comparing the results of this model with the other quarter of the experimental data, the accuracy of this model was examined. key words: One-Part Alkali-Activated Slag Concrete-drying shrinkage- Analytical model of drying shrinkagecompressive strength