Due to many vast application of C- C, C- N, and C- S bond formation in the areas including natural products, herbicides, dyes, agrochemicals, and pharmaceuticals, there has been a great interest in developing new synthetic methods. Herein, the application of Pd (II) complex containing dibenzylated nicotine with general formula [DBNT][PdCl 4 ] was studied in different reactions. First, the activity of this homogenous catalyst was examined through Suzuki- Miyaura reaction. The conversions under optimized conditions of using KOH as base, PEG-200 as solvent at room temperature were excellent and also formation of biphenyl as by-product in most cases was not detected. In the next part, synthesis of aromatic ketones with this catalyst was performed via cross- coupling reaction of arylboronic acids with aromatic and aliphatic acid chlorides. The desired products were obtained in excellent yields at room temperature within short times in the presence of K 2 CO 3 as optimized base and CHCl 3 as optimized solvent. In the next part, the carbon-nitrogen cross coupling reaction of aryl chlorides, bromides, and iodides with aromatic and aliphatic amines was performed at 120 o C, in the presence of KOH and DMSO. Results showed that this catalyst is active and efficient for amination reaction to get good conversions. Finally, we investigated the application of this catalyst in the synthesis of symmetrical diaryl sulfides. The conversions under optimized conditions of using KOH as base, DMSO as solvent at 120 o C temperature were good.