Study area is located in the Khoor-Jandaq metallogenic zone, in the east of Isfahan province of Iran . Studying of specifications of resources, general particulars of metallogeny zone and regional geology result Conception model of different mineralization. In this research, at first a spatial-digital database is prepared from all data source include remote sensing, geology, geochemistry, aeromagnetic, structural maps and existing mineral resources. For extraction of various alteration related whit mineralization, different methods of image processing is used as band ratio, relative absorption band depth, spectral angle mapper, spectral feature fitting and spectral index. Several lithological units are produced from geological maps (1:100000 scales) for integration model, then weight of each unit was determined using conceptual model. Aeromagnetic data is obtained in 1974 to 1977, processed with analytical signal and reduce to the pole techniques and used for potential mapping. Geochemical layer is prepared from anomaly haloes of various elements such as Cu, Pb, Ni, Ag, and Hg that was identified by Russian Technoexport Company. Structure controllers resulted from geological maps 1:100000 and by processing Aster images. For optimization usage of structure in composite model, two layers, buffered structural and lineament density maps were presented. In the next stage, an integrated analysis of different exploration layers were used by using Fuzzy Logic and Weights of Evidence methods, to map high potential regions (copper, lead, zinc, etc) for further exploration. In this method, two different models of fuzzy integration designed for generation of Fe-Mn and Poly metal potential maps. Conformity and comparison of potential maps resulted from both models; It appears that in the Central and Western part of the study area there are high potential zones associated with poly metal mineralization and in the Eastern zone relate with Fe-Mn mineralization. Field follow-up exploration in the Central zone confirmed the presence of poly metal mineralization as well as a large area of K-feldspar which need further detailed exploration. Key Words Mineralization, Synthesize, Integration model, Fuzzy Logic, Weights of Evidence, Khoor-Jandaq