Oneof the richest poly-metal ore deposit metallogenic zones in the metallic Uremia-Dokhtar, in which over several mineral and poly-metal ore deposits have been discovered in the vein and porphyry which svggests investigating and exploring ore deposits of this type in these zones type. The target area is located within 90 kilometers South-East of Isfahan and 40 kilometers South-East of Kuhpayeh. In this area, studies have been done under industrial dust, kaolin, and showed that due to the high level of iron oxide (abundant pyrite) and silica it's quality is not appropriate. According to some evidences, such as silica streaks, high grades of molybdenum and copper, porphyry type phyllic alteration and silica and many other minor evidences, it seems that the are acontains a hidden upper part porphyry kaolin system and in eastern part of the exploration area there is hybrid silica with poly-metal mineralization of copper, lead, zinc and silver which require precise exploratory studies. For this, the aim of this thesis is to examine poly-metal deposit mineralization controllers of Kalchuyeh in the South East of Kuhpayeh. Relevant studies include geology, Remote Sening, geophysics and geochemistry in the region and area which are applied as follows. At the beginning of the attempt, mapping of large-scale geological area (Map 1: 100,000 Kajan) and topography (1: 250,000 Naein and Isfahan) and studies of geology, lithology, mineralogy, are compared with other mineral ore deposits in similar areas. Studies have been done using remote sensing data from ASTER satellite. In order to identify zones of alteration associated with mineralization and also investigating the possibility of similar mineralization in Kalchuyeh, after pre-processing images of the study area by ASTER images, the final processing has been done by applying the methods of the bond ratioing, the least Ls-Fit regression squares and color combination images. Geophysical studies include acquiring geophysical IP / RS data applying bipolar – bipolar arrangements, electrodes' distance of 10 and 20 meters, preparation and data processing using RES2DINV application and creating the appropriate outputs and interpretation of the results. Geochemical studies include preparing analyzed examples of 44 elemental and doing statistical studies, elements' frequency charts and relation, the study of mineralization and cluster analysis of mineralization in the study area. Finally, using a combination of all the results of geophysical, geochemical and geological exploration activities a strategy is suggested and concluded for prospecting exploring such deposits.