Thiocyanate selective electrode has been made by using [Cu(Me-Sal) 2 dpt](II) as a neutral ionophore in the PVC membrane. The electrode possesses the advantages of very wide range of concentration to thiocyanate from 1.0×10 -5 to 1.0×10 -1 M, low detection limit (8.1×10 -6 M), Low response time ( 15 sec), wide pH independent range (3.5-10.5) and, specially, good selectivity over the wide variety of other anions. The proposed electrode was used for the determination of thiocyanate in the smoker and non-smoker saliva samples. A PVC membrane with 4-hydroxy salophen as an ionophore along with sodium tetraphenyl borate (NaTPB) as an anion excluder and dibutyl phthalate as a solvent mediator in the ratio of 28.7:3.3:63.2:4.7 (w/w) (PVC–NaTPB–DBP–Ionophore) exhibits good properties with a Nernstian response of 30.1 ± 1.0 mV per decade for Cd(II). The electrode has wide working concentration range of 1.0 × 10 -6 – 1.0 × 10 -1 M Cd(II). The limit of detection is 8.4 × 10 -7 M Cd(II). It has a fast response time of 20 s and the electrode can be used in the pH range from 2.8 to 8.1. The proposed electrode has been used for determination of Cd(II) ion in water samples