: Zafar-Ghand porphyry Cu-Mo roperty is located at 90km east of Isfahan and 22 km south of Ardestan. As it is located in Orumieh-Dokhatr magmatic belt, it could have high potential for Cu mineralization and therefore, recognition and investigation of mineralization system is necessary. Zafarghand property was identified by using Aster satellite imagery data. After ground control and observation of surface evidences of copper mineralization and alteration, associated with porphyry copper mineralization, follow up exploration were performed in this area. In order to study lithology, mineralogy, rock texture characterization and identification of leached alteration zones, 13 samples were taken from altered rock units and after preparation of thin and polished sections, these sections were studied. Finally, after obtaining the results, geological mapping at scale of 1:5000 was prepared. The lithological and mineralogical studies indicated that the major rocks are comprised of igneous rocks with the composition of rhyolite and rio-dacite. Minerals, observed in the area, are consist of pyrite, chalcopyrite, sphalerite, sericite, hematite, geothite and malachite. The alteration of area were created due to impact of hydrothermal solutions and mostly are associated with subvolcanic rocks of the area. They consist of phyllic, argillic, propyllitic, potassic and siliceous alterations. The geochemical studies were followed by taking 250 systematic rock and soil sample on a 100m by 100m grid. At the same time, infill samples were taken, in the central of porphyry system, on a 50m by 50m grid. After analyzing the collected samples for 43 elements by ICP, basic and multivariate statistical studies were carried out. The results showed strong concentration of Cu and Mo in the central part of the dioritic intrusion. In order to separate anomalies from the background, the stroked="f" filled="f" path="m@4@5l@4@11@9@11@9@5xe" o:preferrelative="t" o:spt="75" coordsize="21600,21600" and gap statistic methods were used and showed high correlation with each other. The geophysical studies were carried out by using magnetic and IP/RS surveys. The magnetic survey were consist of 22 profiles on a grid of 60m by 30m. Then we carried out daily and topographic corrections on the data. After processing the data and creating different magnetic maps, the results indicated a high magnetic anomaly related to magnetic minerals associated with mineralized potassiclally altered diorite intrusive, located in the central part of the South Zone. The IP/RS survey were consist of 7 profiles, mostly located in the South porphyry center. A two dimensional inverse modeling was performed and then a three-dimensional model was prepared. The modelling showed the boundary of sulfide and oxide zone, argillic alteration as well porphyry body. Finally, different exploration layers at the South Zone were integrated using three methods of Independent Component Analysis (ICA), Weighted Overlay and Fuzzy Logic. The layers were integrated by ICA and Weigthed Overlay were consist of lithological units, geochemical and geophysical anomalies. In addition to the previous layers, alteration, iron oxide and fault density were integrated using Fuzzy Logic method. Although, all the three methods confirm the results of each other, but the ICA and Weigthed Overlay method showed a better correlation. Eventually, the intersecting areas of the three integrated method were determined and high potential reas were proposed for test drilling.