Hydrocarbon seeps through the earth’s surface can lead to an exploratory process. Hydrocarbon seeps may appear on the earth’s surface through joints, gaps, fault planes, unconformities, or bedding planes. The effect of permeability of hydrocarbon microseepage in the fields is observed through remote sensing and GIS. This study is analyzed based on alteration, petrology, and structural analysis. Moreover, the necessary modifications and enhancements and proper pre-processing (on the Aster and Sentinel 2 Reflectance IAR data and Landsat FLAASH 8 data), and the analysis of the effect of vegetation on Dehloran field, that is located 22 kilometers from the southwest of Dehloran County and has the same structure as Abou Ghraib field, and Cheshmeh Khosh oil field that is located 52 kilometers from Dehloran County are carried out. Based on these multispectral images the band ratio, SAM, least squares, PC, and Crosta are used for soil alteration while the color composite, optimum index, and false color composite methods are used for petrology. Besides, filtering is used for faults and lineaments. Finally, Landsat 8 data fusion in GIS is used for the optimum hydrocarbon potential. In the identification of the argillic alteration in Dehloran field, Aster multispectral data, Crosta method (PC4) in Landsat 8, the least squares method (Cheshmeh Khosh field), and iron alteration with 6 to 5 band ratio in Landsat 8 and 11 to 2 band ratio in Sentinel 2 led to satisfactory results. For the lineaments and faults, the best filter type is directional filter on PC1 and the panchromatic band. Finally, the petrology, alteration, geobotany, and structural data are fused using the fuzzy logic model and Landsat 8 data in GIS and an efficient hydrocarbon potential map is obtained. These areas are adjacent to structural traps, and Dehloran anticline and folds around Cheshmeh Khosh indicate the presence of a fault. Moreover, faults contribute to hydrocarbon migration in the areas.