Previous studies have shown that Pomegranate extract in addition, by-product compounds of Pomegranate as peel, skin and seed have a most active biogenic compounds. In this study, the effects of pomegranate pulp as a rich source of phenolic antioxidants and pomegranate seeds as a rich source of conjugated fatty acids on production performance and oxidative stress on dairy cows in transition period has been studied. For this, 27 Holstein cows in late pregnancy with an average body weight 716 ± 70 and the average body condition score 43.3 were chosen. Project includes 3 treatments with 9 replications. 4 heifers and 5 cows multiple calving to each treatment was given. In this experiment, animals from 25 days before the expected calving date to 25 days after calving received diets. Experiment was conducted in a completely randomized design. Treatments include (1) control diet (no byproducts pomegranate), 2- diet with pomegranate seeds and 3- pomegranate pulp diet (mixed peel and core), respectively. The results showed that animals received that diets contain pomegranate pulp after calving, milk production and energy corrected milk were also cows received pomegranate pulp lower concentrations of NEFA, BHBA, triglycerides and malondialdehyde. Cows that were given pomegranate pulp rumen acetate content, antioxidant capacity, superoxide dismutase and ratio superoxide dismutase to hemoglobin were higher than other cows. In general, this nutritional strategy could improve performance, blood metabolites status, markers of oxidative stress and energy balance indexes. Keywords : energy balance, transition, pomegranate, oxidative stress, conjugated fatty acids