Extension of nanotechnology have led to progression and development in various scientific and commercial fields. Textile industry is not deprived of the benefits of nanotechnology. The use of nanoparticles is very common in the textile industry, Titanium dioxide is one of nanoparticles which has many different applications in textile industry. Two important properties of this nanoparticle that make it very efficient and useful are the Photocatalyst and superhydrophilicity properties. Polyester polymer based on polyethylene terephthalate has a compact structure and partially crystalline. Static electricity which lead to attraction of dust, Difficulty in dyeing Process, Discomfort polyester textiles and clothing (due to low ability to absorb water and perspiration) are problems of common fibers. In this study, the two Photocatalyst and hydrophilic properties of titanium dioxide nanoparticles were used in order to achieve suitable dyeing polyester fabrics. First, surface roughness is created on the surface of polyester fabric by alkaline hydrolysis treatment, and then by Pad-dry-curing process the solution with different amounts of titanium dioxide nanoparticles which obtained in the ultrasonic bath in the form of dispersions in water, were fixed at different temperatures on the surface of polyester fabric in the Astntr machine.Taguchi method was used for experimental design In order to achieve optimal experimental conditions. After pad-dry-curing Process and determination of optimal experimental conditions, treated and untreated samples were dyed in the boiling temperature by Disperse Blue 56. Using of K/S samples in the wavelength of maximum absorption, investigated the absorption rate and the Kinetics of dyeing color samples. Also light and washing fastness of samples were investigated. Dyeing process showed that although the adsorption and dyeing rate of polyester treated with titanium dioxide nano particles increased significantly than untreated polyester fabric dyed without carrier, but the carrier method, demonstrated higher adsorption and dyeing rate. Washing fastness of untreated polyester that is dyed with carrier and without carrier was similar to washing fastness of polyester treated with titanium dioxide nanoparticles. Light fastness of treated polyester that dyed without carrier is lower than two other samples. This reduction can be attributed to the presence of titanium dioxide nanoparticles and catalyst properties of the nanoparticles. Also using a test absorption time and wettability properties of untreated and treated polyester with titanium dioxide nanoparticles were studied. The results show a significant increase of wettability properties of fabrics treated with titanium dioxide nanoparticles than the untreated. The increase of wettability, with irradiated UV light is more intense. Tensile strength experiments showed no significant change in strength of polyester treated with titanium dioxide nanoparticles. Finally, self-cleaning experiments, was done by methylene blue and UV radiation. The results showed that the presence of titanium dioxide nanoparticles on the surface treated polyester, leads to significant improvement of this property. XRD, FTIR, SEM Tests also was performed on the samples. XRD samples showed that increasing crystallite polyester treated with titanium dioxide nanoparticles. SEM shows the surface roughness polyester fabric treated compared to untreated. FTIR samples showed the presence of titanium dioxide does not reaction with the treated polyester fabric. Key words: titanium dioxide nanoparticles, alkaline hydrolysis, polyester, dyeing, self-cleaning