Asphaltene precipitation and sedimentation is one of the main problems in the oil industry, which attracted the attention of many researchers. Precipitation and sedimentation of Asphaltenes can lead to many problems, such as closing the reservoir's pores, and also the ability to change the wettability of the reservoir from hydrophilic to hydrophobic. Therefore, understanding the factors affecting the formation of Asphaltene sediments can help us to prevent these problems. In the past, factors such as changes in pressure, temperature, and crude oil composition have been studied and the effects of these parameters on the Asphaltene stability are almost clear. However, during the advanced methods of EOR and injecting smart water, an emulsion of water-oil is formed, whose effect on the stability of Asphaltenes is still unknown and unclear. Despite the incompatibility of water and oil, these two can form emulsions and affect the deposition of Asphaltene. Therefore, the study of two-phase flow of oil and water on the Asphaltene Precipitation phenomenon is very important. In this study, the effect of low Brine and silica nanofluid on the Asphaltene precipitation onset point has been investigated using indirect method. First, the effects of emulsion water in two volumes of 25% and 50% on the stability of asphaltene have been investigated. Then, samples of emulsified water with NaCl, KHCO 3 , Na 2 SO 4 , CaCl 2 and MgCl 2 salts in 5000 ppm and 15000 ppm of concentrations in two volumes of 25% and 50%, were prepared. Then, the effect of each of the samples on the stability of Asphaltene in crude oil has been investigated. Finally, the effect of the presence of 0.1 Wt% nanosilica and brine were investigated to better understand their mechanism of Asphaltene stability or instability in 5000 ppm of salt and 25 Vol% of them. In general, this study was conducted with the presence and absence of water.