Magnesium fluorapatite (MFA) with different amounts of alumina (0, 10, 25 and 50wt %) were milled in order to obtain biphasic composites. The effect of alumina addition associate with applied two–step sintering (TSS) method, on mechanical properties and densification was investigated. Taguchi method was used to design of experiments and the results were evaluated with the analysis of variance (ANOVA). Variable parameters include: initial temperature and the temperature and the time of secondary stage. X-ray diffraction was used to phase study during sintering. Scanning electron microscopy (SEM) was used to estimate particle size and structural changes in MFA/alumina composites. To evaluate the bioactivity of bulked samples in simulated body ?uid (SBF), Fourier transform infrared spectrometer (FTIR), Inductively-coupled plasma (ICP), spectrometry, scanning electron microscopy (SEM) and X-ray diffraction (XRD) were applied. Result showed that, fracture toughness and hardness of composites increased linearly by addition alumina. The fracture toughness and hardness of MFA-A1 2 O 3 composites is reached maximum values of 5.82±1.05MPa m ½ and 22.09±3.5 GPa, for MFA/50 % alumina composite, respectively. In all of the composites, MFA decomposed to ?-tricalcium phosphate (?-TCP) via used TSS. Moreover, at 1300 o C, composite is completely decomposed and MFA peaks were disappeared. The formation of apatite layer is occurred on the surface of all composites. In MFA/10% alumina composite, the accelerate growth of apatite during immersion in SBF was observed. In purity MFA, the growth of apatite was occurred from 7 to 28 days immersion in SBF continuously. Keywords : Mg-fluorapatite, Composite, Alumina, Two–step sintering, Mechanical behavior, Bioactivity, Taguchi Method.