A large amount of water is used in the most processes of mineral processing. Water recovery from solid is needed to reduce operating costs. In dimensional stone processing factories due to lack of water resources, Pollution caused by wastewater and Its environmental aspects, needed for clean water to improve the quality of cutting and polishing stones and prevent damage to factory equipment, it is essential to use solid-liquid separation processes for wastewater purification and reuse. In this research, wastewater treatment of granite stone processing (Khoram nou) was investigated by using anionic and cationic flocculants with considering the parameters affecting on the wastewater treatment process. Experiments conducted with anionic flocculants showed that this types of flocculants do not have an adequate efficiency for purifying of granite wastewater. Increasing the concentration of anionic flocculants and the rate of agitation speed will aggravate the refining and sedimentation conditions. The most suitable result was obtained from low charge anionic flocculant with a stirring rate of 200 rpm, a flocculant concentration of 0.2 g / l and with 6 minute flocculation time. After 12 minutes of sedimentation, 65.1% impurities was eliminated. The results obtained from cationic flocculants indicated a very high efficiency of these flocculants for the refining of granite wastewater. For this types of flocculants, the highest percentage of removing impurities after 6 minutes of flocculation was obtained from low charge cationic flocculant with a stirring rate of 600 rpm and a flocculant concentration of 0.2 g/l. The amount of turbidity dropped to 99.36 after 12 minutes. By considering the obtained results and determining the appropriate flocculant, low charge cationic flocculant was used for investigating parameters such as flocculation time, temperature and effect of the use of a baffle. The results of flocculation time showed that with increasing time, more suspended particles were eliminated. The results related to the effect of temperature on flocculation showed that increasing temperature improved the flocculation. The use of Baffle also improved the mixing condition and After 12 minutes, 99.82% of the turbidity and suspended particles were removed from the wastewater. The turbidity tests were performed using low charge cationic flocculant at 0.2 g/l concentration, 400 rpm stirring speed and with 6 minute flocculation time for investigation of turbidity test. The results showed that, after 12 minutes, 99.6% of turbidity was eliminated. The results obtained using the UV-Visible spectrophotometry in the same conditions indicated that 98.95% of turbidity removal was achieved. These results indicated that two methods of measuring the amount of impurities contained differences by marginal discrepancy and as a result, the UV-Visible spectrophotometry has a good efficiency to analyze the sedimentation tests and determine the water quality for dimensional stones processing. The results of filtration tests show that filtration time decreased and filtration rate increased by using cationic flocculants. In this case, the filtrate clarity is greater than pulp with simple sedimentation and anionic flocculation. Additionally, cake moisture by using cationic flocculants was less than when anionic flocculants were used but had higher moisture compared to the simple sedimentation