Waterways and rivers are very varied in nature and almost in all of them flow is turbulent and hydraulically rough, also vegetation as a natural factor exists in these environments, typically. In general, flow conditions in coarse beds are very complicated and the presence of vegetation increases this complexity by producing an additional turbulence. In this research turbulent flow characteristics for different cobble concentrations in the bed and the presence of vegetation in the channel wall including velocity profiles, location of maximum velocity, inner boundary layer region, outer boundary layer region, Reynolds stress distribution, turbulence intensity and turbulent kinetic energy were studied. Experiments were carried out in an 8 m long, 40 cm wide, and 60 cm high re-circulating flume at the Hydraulics Laboratory of agriculture faculty of Isfahan University of Technology using cobbles with median diameter 85 mm under uniform flow with zero bed slope. Experiments were performed in two series, in the first series channel walls were without vegetation and in the second series conditions were same as before but straws were placed in the channel walls. Velocity profiles were taken in the reach that flow was fully developed, these measurements in addition to the central axis of channel were performed in several distances of the wall. Data of taken profiles by ADV using WinADV software were analyzed. This study shows that the distribution pattern of turbulent flow characteristics by changing the cobble concentration in the bed, remains constant but the values of these parameters in different relative depths alter, In this way at higher concentrations, velocity values in inner layer are less and in outer layer are greater, While by increasing cobbles concentration, the shear stress increases in inner layer and decreases (to the location of maximum velocity) in outer layer. In addition, wall vegetation affects on turbulent flow structure in cobble bed by increasing secondary currents and turbulence. Also this vegetation changes procedure and the values of turbulent flow parameters by momentum absorption for close distances to wall vegetation, so that dip parameter, high credit limit logarithmic law, turbulent intensities and turbulent kinetic energy increase in this state. Keywords : Velocity Distribution, Reynolds Stress, Cobble Bed, Wall Vegetation