To study plate heat exchangers, the configuration is one of the most important parameter on the heat exchanger efficiency. One of the advantages of the plate heat exchangers are ability to fit properly with any process types. Since the gaps between plates in the plate heat exchanger are very small. The flow is turbulent even at very low Reynolds numbers. In this project, three types of corrugated plate heat exchangers and various configurations with 24 channels were investigated computationally using Fluent. Different parameters and modeling were examined on performance of the heat exchanger. The RANs equations together with the standard turbulence equations were solved using a Finite-Volume technique that employed in Fluent. Results of simulations show that the heat exchanger performances are improved by increasing the number of passes and number of channels for the countercurrent flow. However in this case, all configurations have not enhanced equally the performance of the heat exchanger. This means that both the parameters need to be increased Simultaneity to increase performance. Moreover the effect of the second fluid is more important than the number of passage in same cases. The number of passage may increase heat transfer and flow rate; however pressure loss will also increase. Furthermore, the flow rate cannot be distributed equally in these passages. Finally, it is also observed that the heat exchangers with vertical flows perform less then similar configurations with cross flows.