Genetic diversity of wild common carp ( Cyprinus carpio ) in the Anzali wetland by sampling from 100 rood fish from five stations (20 individuals from each satation), including four from Anzali wetland (Siah Khesheim Protected area ??, Selkeh and Sorkhankol wildlife shelters and Abkenar area, plus one satation located at the Anzali wetland estury to the Caspian Sea were analysed using four microsatellite loci CCa67, MFW 16, MFW 26, MFW 6. The mean observed and effective alleles number were 8.95 and 5.92 respectively. The mean observed and expected heterozygrosity were calculated as 0.972 and 0.817 respectivily. The highest and lowest inbreeding coefficients were measured for the fish belong to Sorkhankol (-0.114) and Selkeh (-0.273) stations respectivily. The highest and lowest Fst values were calculated between estury and Selkeh (0.096) and estury-Sorkhankol (0.04). The mean Fst value was 0.098 showing signification genetic differentiation among satations ( p 0.05). o Hardy-Weinberg equilibrium was measareable for any station-loci tests ( p 0/05). AMOWA showed the highest genetic diversity (91%) whitin populations while the lowest one (9%) was observed between them. Dendrogram showed two seprate branches for the common carp populations in the Anzali wetland including a) Siah keshim, Sorkhankol and estuary, b) Selkeh and Abkenar. The results of this study can be used for optimizing restocking programs of the common carp in the north of Iran. Keywords : Anzali wetland, Common carp, Heterozygous, Genetic distance.