In this project, a series of novel thermally stable polyamides (PA)s based on chiral amino acids moieties such as S-valine, and L-phenylalanine were synthesized and some physical properties of them were investigated. For this purpose at first 5-[3-methyl-2-(1,8-naphthalimidyl)butanoylamino] isophthalic acid and 5-(3-phenyl-2-tetrabromophthalimidylpropanoylamino)isophthalic acid were prepared in three steps. These monomers have chiral amino acids moieties and readily can be converted to bioactive polymers. Also polymers based on brominated monomer 105 have flame retaredncy property. These polymers were synthesized via two different methods, conventional heating as well as microwave irradiation in ionic liquid (IL) and traditional solvent. NMP/TPP/CaCl 2 /Py was used as a condensing agent for direct polycondensation of monomer 105 by reflux conditions whereas in IL as a media used only triphenyl phosphite. The use of IL as solvent and catalyst for polyamidation reaction eliminate the need of volatile and toxic solvents. These compounds were characterized by FT-IR, 13 C-NMR, 1 H-NMR, UV-Vis, fluorescence spectroscopy, specific rotation, elemental analysis and thermal gravimetric analysis/derivative thermal analysis and differential scanning calorimetry. These polymers have flexible amino acids and bulky pendent groups and consequently reduce packing efficiency of polymer chains, therefore have very high solubility. Also thin traarent films of these polymers can be prepared.
