A novel magnetic nano-adsorbent has been synthesized by the covalent immobilization of poly (acrylic acid) (PAA) and a thiosalicylhydrazide (TSH) agent on the surface of Fe3O4 nanoparticles.The prepared magnetic nanoparticles (M) were characterized by Scanning electron microscopy (SEM), Atomic force microscopy (AFM), FT-IR spectroscopy, X-ray diffraction and Vibration samplemagnetometer(VSM).The SEM images showed that the diameters of the Fe3O4@PAA@TSHM are about 10-35 nm.The ability of the Fe3O4@PAA@TSHM for removing heavy metal ions (Pb2+, Cd2+, Cu2+, Zn2+ and Co2+) from aqueous solution was studied and the effects of thesolution pH, contact time, metal ions concentration and background electrolytes on the adsorption characteristics of the modified M were investigated. The results showed the conditions of solution pH=5.2, 100 mg.L-1initial concentration ofheavymetal ion ,1 g.L-1 adsorbent andtime of 40minutes dose the optimum conditions for this application. Finally, adsorption process was investigated with Langmuir and Freundlich isotherms. The experimental adsorption equilibrium data were fitted to Langmuir adsorption and the maximum adsorption capacities of Pb2+, Cd2+, Cu2+, Zn2+ and Co2+ were found to be 188.7, 107.5, 76.9, 51.3 and 27.7mg.g-1adsorbent, respectively. The adsorption was fairly rapid, because it doesn’t take more 40 minutes to reach the equilibrium state and kinetic data were precisely fitted by the pseudo-second-order model. The assumption that the metal ions adsorption is due to complex formation between active sites of the adsorbent and the heavy metal ions was further confirmed by investigating the adsorption isotherms and kinetics.The desorption experiments under batch conditions revealed that the Fe3O4@PAA@TSH M are reusable adsorbent for practical removal of the heavy metal ions. In addition, it was found that presence of amine and sulfur binding sites on the surface of the prepared M not only can significantly improve the adsorption capacity of the adsorbent but also can notably reduce the interferences of the alkaline/earth metal ions. These improvements are most probably due to higher affinity of the sulfur and amine sites of the modified M for complex formation with the heavy metal ions via soft-soft interactions.For testing the ability of the prepared nanoparticles for removal of heavy metal ions from industrial samples was evaluted using different industrial wastewaters from Moham industrial complex, Raad plating company and Iran Aircraft Manufacturing Industrial Company (HESA) and obtained optimum conditions is adsorbent concentration 1 g.L-1, contact time 40 minutes, solution pH=5.2, solution valume 50 mL and stirrerspeed 300 round per minutes that is applied to real samples. The obtained resuls showed that Fe3O4@PAA@TSHM can be used for removal of heavy metal ions from industrial wastes.