In this study, the removal of three types of dyes such as acid yellow 236, Reactive Red 3 and Direct Blue 168 with the tree Moringa Peregrina seeds powder without oil, as an adsorbent, investigated in the batch system and with Experiment of Infra Red were identified forming absorbent functional groups. Removal efficiency of the dye investigated with changing the initial pH (3, 4, 5, 7, 8, 9, 11), the contact time (10 to 300 minutes), the mixing speed (120, 150, 180 rpm), the initial concentration of the dye (10 -50-75-100-150-200-250-300 mg/L) and the absorbent’s mass (0/5, 1, 1/5 2, 2/5, 3 g/L), at about 25 ±2 centemeter . degree. The results showed that the initial concentration of dye, increased dye removal efficiency for all three dyes And increasing the pH, for reactive red 3 and direct blue 168 reduces the dye removal efficiency and increasing the pH for acid yellow 236 increased removal rate about 8 and then removal efficiency decreases with increase in pH. Optimal contact time of acid yellow 236, Direct Blue 168 were obtained 90 minutes and 60 minutes for Reactive Red 3. The mixing speed of 150 rpm was selected for the main experiments. Experiments was designed by Design Expert Software with response surface methodology (RSM). The optimum mode for the three dye such as acid yellow 236, Reactive Red 3 and Direct Blue 168, respectively was obtained for adsorbent: 1/3, 1/25, 1/9 g/L, initial dye concentration: 250, 230, 245 mg/L, pH: 8/2, 3/1, 3/5 and removal efficiency: 86%, 95%, 92%. The results of the fitted constant balance on isotherm models, showed that fixed data balance with regression coefficients higher for acid yellow 236, red Reactive 3 and Direct Blue 168, respectively follows, Freundlich R 2 =0/9563 BET R 2 = 0/9793, Langmuir R 2 =, 0/9599. it is determined that removal of reaction kinetics for, acid yellow 236, Reactive Red 3 and Direct Blue 168, follows pseudo-second-order model fitting R 2 , respectively 0/9999, 0/9996, 0/9372. Key Word : Moringa Peregrina, dye removal, absorption, RSM