Ionic liquids are room temperature liquid compounds. Because of their significant properties such as catalyst stability, recycle ability, low vapor pressure and so on, they have been frequently used as catalyst and solvents in organic chemistry. Melting point of these compounds are below 100 o C. Protic ionic liquids a class of ionic liquids can be synthesize easily by combination of bronsted acids. Protic ionic liquids have proton for hydrogen bonding. Acidic ionic liquids a class of protic ionic liquids can be use them inside of mineral acids. Today the ionic liquids can synthesize with room temperature melting point and this is a good reason for expansion of ionic liquids applications. Here we like to report the synthesized [H-NMP] HSO4 as a novel acidic ionic liquid and studied the applications of this ionic liquid for transformation of some organic functional groups. By using this ionic liquid, we have develop method for functional groups transformation such as acetalization of aliphatic and aromatic alcohols. In this project we used a mild and simple method for acetalization of alcohols in presence of acetic acid and catalytic amount of the ionic liquid. Also we tried the protection of carbonyl groups to thioacetals in the presence of a catalytic amount of acidic ionic liquid under solvent free condition at room temperature. This method was chemoselective for protection of aldehydes and aliphatic ketones. Also we tried the application this ionic liquid for azidation of alcohols compounds have avariety of application such as anti HIV and TB drugs and using of them in click chemistry for synthesize of tetrazols and three azols cycles and so synthesize of amines and their application in organic chemistry. Benzylic alcohols in the presence of this ionic liquid were transformed to the corresponding azide. We used this ionic liquid as catalyst and solvent.This project has some benefits such using an ionic liquid for replacing volatile organic solvent, inexpensive and accessible reagent, mild and simple method, short reaction times and high yields.
