Some disperse reactive dyes were synthesized. The disperse dyes were substituted with chlorotriazine. During the synthesis disperse reactive dyes, the thin layer chromatography (TLC) was applied to monitor the synthesis reaction. After purification of products, The characterization of the new dyes was performed by FTIR and UV-VIS spectroscopies. The products were used to dye nylon and wool / polyester blends. For dyeing of nylon, some kinds of dyeing methods such as one bath-one step and one bath-two steps dyeing were used and their dyeability were investigated with colour strength, degree of exhaustion and fixation. The best results were obtained, when these dyes were applied under acid condition, until level dyeing properties of disperse dyes were produced. When the bath is made mildly alkaline, reaction occurs between dye and fibre and fast, level dyeing is achieved. The dyeing obtained from disperse reactive dyes, have fairly good fastness to washing. The dyeings are stable to heat-setting. Rubbing fastness of the dyings improved, compared with dyeings obtained by disperse dyes. It was shown by optical microscopic, that nylon dyed with disperse reactive dyes have leveling distribution of dyes on the fibre. The results from experimental shows that reaction between the disperse reactive dyes with nylon fibre were occurred e.g. the disperse reactive dyes could not be completely stripped from the dyed fibre using solvents, such as propanol, which completely stripped conventional disperse dyes from the substrate.The resistance of disperse reactive to propanol extraction that suggests that some force other than van der valce adsorption, mechanical retention, or salt linkage is holding the dye on the fibre. Also, when nylon which had been dyed with disperse reactive dyes, was dissolved in o-chlorophenol and the solution precipitated in propanol, the precipitated nylon was coloured, In the case of original disperse dyes, the precipitated nylon were colourless. The above results showed that chemical bonding between disperse reactive dyes and nylon occurred. The dyeing carried out on different wool/ polyester blends by a carrier-dyeing technique. The dyeing behavior of the synthesis disperse reactive dyes o the wool/ polyester blends was assessed. Some of the disperse reactive dyes dyed both components of polyester/wool blends to approximately the same depth (union dyeing). The dyeing obtained had satisfactory fastness properties and showed fairly good dye fixation on the wool componenet of these blends. The suitability of the dyes for printing of nylon has been examined. Maximum colour strength was achieved using neutral paste and also using saturated steam as fixation medium that followed by heating the prints for a short time. After heating at 180?C for a 1 minutes, colour strength of dyes greatly improved. It was found, these conditions were apparently necessary for dye diffusion into the fibre.