In this study, thermoeconomic analysis was performed to calculate and optimize steam jet refrigeration system. This system designed to work with water as refrigerant, because water is known as an environmental friendly fluid. Different configuration of system including, preheater, precooler and muliejector suggested and compared to define the most suitable economical configuration for the system operational in warm climate. Five configurations have been simulated thermodynamically in Engineering Equation Solver (EES) under the condition of 5 kW cooling load, sun radiation of 850 W/m 2 and the ambient temperature of 35 °C. Similar condition considered for all of the configurations as the start point. In this condition, the temperature of evaporator, condenser and generator are 7 °C, 45 °C and 85 °C. As the cost of heatexchengers bounded to their size, the appropriate equation carried out from heat transfer equations to size them. Thermodynamic simulation performed completely so that the exergy of all streams carried out for all of suggested configurations. The exergic efficiency and coefficient of performance of all configurations calculated before any attempt to start economical evaluation. Thermodynamic calculation showed that the forth configuration has the maximum coefficient of performance (0.253) based on working condition. Thermoeconomic calculation performed after exact and detailed thermodynamic calculation of all the suggested configurations. Evaluation of exergy and other thermodynamic properties of streams were conducted in these configurations. The average exergy cost method selected to extract economical calculation of system as one of the more suitable method in economical calculations based on exergy in systems of energy. Detailed economical calculation carried out for all streams and it was shown that cost of final product is much lower for model two and four in contrast to model one and three. The cost of final product gained 76.71 $/GJ in model number two which is the minimum value between all of suggested configurations. Accordance to the thermodynamic performance and the investment cost of this model, it was selected for optimization. Optimization performed in an iterative procedure and the result shown that this model will reside in thermoeconomic optimal condition by choosing 88 °C, 43 °C and 5 °C for generator, condenser and evaporator; respectively. In optimal condition, there was a reduction in cost of final product about 1.8% and there were significant reduction in investment cost of components and cost of exergy destruction and exergy loss about 20.57% and 39.1%; respectively, which shows the importance of economical evaluations of energy sytems. Iran is really wealthy in solar energy and usually there is no cloudy day throughout the warm seasons of year in center and south places of this country. On the other hand, a large amount of energy consumed in air conditioning applications of residential homes and office buildings annually. In this situation that lack of energy is a main problem, designing solar driven systems would be a suitable answer to this drawback which helps to save a large amount of electrical energy. Economical considerations help to reduce costs in air conditioning applications, too. Keywords: Air conditioning, Ejector refrigeration system, Thermodynamic, Exergoeconomic, Solar source.