In light and heavy vehicle to adjust undesirable effects arising ripples of road surface, suspension system uses. This project has been defined for the requirement of multi usage vehicle with target of design and optimization of desirable suspension system for this vehicle. In third chapter, after primary review of this object and vehicle dynamic model, front and rear suspension system has been designed and manufacturing plans of suspension system have been presented. At next chapters, there are simulations of road profile and dynamic model in MSC.ADAMS software. Then, design of experiments by taguchi method, modeling with use of Neural Network model and stabilization vehicle handling with genetic algorithm by means of MATLAB7.4 have been done. At the end, design and topological optimization of rear suspension system in the multi usage vehicle by ANSYS software have been studied and result percent reduction of primary wrought of vehicle have been given.