Due to many vast application of C-C bond formation in the areas including bioactive compounds, natural products and high performance materials, over the past few years, the C-C coupling reactions have become a versatile tool in organic synthesis. Some of the most efficient methods in this category are Heck, Suzuki, homocoupling and cyanation of aryl halides. These reactions often performed under elevated temperature; therefore all of the reaction partners should have high thermal stability. Application of microwave irradiation for promoting reaction condition, nowadays, has become a versatile tool in organic synthesis. This technique can cause to increasing the yields of reactions, decrease the required time for completion of the reactions and also has advantage for enabling reproducible and scalable chemistry development in research laboratories and industrial processes.Herein, the application of four different palladacycle systems as pre-catalyst in the formation of C-C bonds were examined under microwave irradiation and their results were compared with reactions under conventional heating conditions in an oil bath. Primarily, the activity of [Pd(C 6 H 4 CH 2 NH 2 -k 2 -C-N)PPh 3 MOY]OTf complex, 1 (MOY = 4-methoxybenzoylmethylenetriphenylphosphoraneylide) was investigated in the Heck-Mizoroki reaction under conventional heating and microwave irradiation conditions. The complex was active and efficient catalyst for the Heck reaction of aryl halides. The yields were excellent using a catalytic amount of complex 1 in NMP at 130 °C . In comparison to conventional heating conditions, the reactions under microwave irradiation gave higher yields in shorter reaction time. Also, application of this catalyst in the homocoupling reaction of various types of aryl halides was examined under MW irradiation and optimized reaction condition. Again, the complex was active and showed high efficiency in the formation of C-C bonds. The reactions were carried out using DMF as solvent and 0.1 mol% of catalyst at 120 o C. Then we used four different palladacycles, 1-4 in the cyanation reaction of aryl halides under MW irradiation and compared their results with each other. Reactions were performed using K 4 [Fe(CN) 6 ]in DMF as optimized solvent and 0.5 mol% of palladacycles at 130 o C. The yields were very good to excellent and the required time for completion the reactions is very short. Finally, we investigated the application of palladacycle complex 3 in the Suzuki reaction of aryl halides under microwave irradiation condition. The resulted yields in this case were very good to excellent and the reaction times were reduced from hours to minutes using microwave irradiation.