Fresh water and energy are one of the most basic human needs today, due to population growth, increasing the level of living conditions and climate changing, by paying attention to these two basic things, replacing the source of fresh water is important. Many actions have been conducted to resolve this issue, including use of sea water and desalination of it by the process of distillation, which requires a lot of energy. Fossil fuels are good sources of energy, but finishing the source of fossil fuel in the near future and the environmental problems caused by their burning; they are not a good alternative. Therefore, there should be a more suitable candidate way to replace fresh water. The vacuum membrane distillation is a process of separating liquid solutions based on the pressure difference, which can lead to water evaporation at low temperatures and reduce the water and energy stress (which our society faces) Vacuum membrane distillation is used for applications such as desalting, removal of small pollutant molecules and the recovery of other components. In this dissertation, membranes with different percentages of PVC and PVP additive were fabricated by phase separation method (LIPS VIPS) with different thicknesses followed by testing in vacuum membrane distillation cycle. Optimum PVC membrane with the permeate flux of 22.83 kg/m2 through the vacuum membrane distillation was obtained, and characterized by thickness measurements, total porosity, water angle, LEP and FE-SEM. Keywords : Membrane Distillation, Vacuum Membrane Distillation, Membrane, Phase Separation, Electrospinning, Desalination