Kidney tralant or hemodialysis or peritoneal dialysis treatment is used for End Stage Renal Disease patients. The Iranian Society of Organs Tralanation has informed that there are 25,000 patients with chronic renal failure in November 2015 in Iran, who are waiting for kidney tralant. Only 46% of these patients succeed to tralant and 51% are under hemodialysis treatment. So the most important alternative for kidney failure treatment is hemodialysis. Even though the removal, during the time of dialysis is not dissimilar to the removal provided by the normal kidney, the overall clearance of urea is only about 20% of that of the normal kidneys. This is because patients commonly, only receive dialysis for 12 hours or less a week whereas the normal kidney labors every second of the day. Also intradialytic hypotension is a common and frustrating complication of hemodialysis and Up to 50% of mortality risk in the dialysis population is attributable to cardiovascular disease. In this study, it was decided to build cylindrical poly sulfone nano fibous filter because of higher efficiency of Nano-filters. The goal is to produce a compact size and effective filter for using in the wearable artificial kidney (WAK) and dialysis done continually while allowing mobility. It is hoped that the continuous dialysis will improve the quality of life for kidney patients and keep them healthier. For this purpose a collector were made with 3-axis diameter of 3, 6 and 9 mm. the membranes was made with three inner diameter of 3, 6 and 9 mm and Nano-fibers membranes was spun of poly Sulfone at a concentration of 11.5% and DMF and THF solvent at a ratio of 70/30. Spinning distance was 12 cm and spinning voltage was 12 kV and feeding speed was 0.01 ml per minute.Then the device was made similar to the dialysis machine. And dialysis procedures with these membranes were tested to remove urea and creatinine from the it's solution in duration of 1.5, 3, 5, 7, 12 and 24 hours. Also Patients' blood duration of 1.5, 3 and 5 hours was tested. The results showed that the membrane orientation is decreases by reducing the rotational speed of collector.Also, nano fibers diameter and membrane filtration efficiency increased. Therefore, the lowest rotational speed of collector was as well as as the optimal speed. Subsequently, membranes with inner diameters of 6 and 3 mm were produced at the lowest acceptable thickness with satisfactory strength and uniformity. Finally, SEM images showed that by reducing the inner diameter of the membrane from 6 to 3 mm the membrane thickness reduces from 41 to 15 microns and the diameter of the Nano fibers increases too. Also experimental results showed that the urea and creatinine removal in membrane with diameter of 3 mm at 1.5 hours duration is more than 60% and it is acceptable in comparision to other studies. But the results of membrane with 6 mm diameter are not acceptable. Therefore, membrane with 3 mm inner diameter was selected as a final sample. Eventually 3 patients' bloods were tested with chosen membrane. The results evident that the creatinine and urea removal rates at 1.5 hours duration were respectively %70.9 and %80.1. Key words:End stage renal deasis, Creatinine, urea clearance, Chronic renal failure, hemodialysis, kidney tralant, Nano fibers