Nonlinear optics is one field of optics science which was presented after laser invention . The nonlinearity implies from nonlinear response of material in laser coherent light-matter interaction . In fact , when the material illuminated by laser light , we face nonlinear properties resulting from high orders of electric field in polarization relation . Inherently , the materials have very weak nonlinear nature , so in several last decades , to increase nonlinear efficiency different techniques such as novel materials or artificial structures have been proposed . One of the proposed materials is combination of III-V semiconductors layers to compose multi-quantum well structures . These structures excite nonlinearity using intersubband transitions , and exhibit one of the largest bulk nonlinearities among all condensed-matter systems . However , these heterostructures have a significant drawback; their nonlinearity can be achieved only for normally polarized light to the layers . To remove this limitation , the plasmonic metasurfaces have been used . In linear optics , the metasurfaces have a variety applications in wave engineering such as adjust amplitude , phase , wavefront and polarization of transmitted and reflected waves , for this flexibility these can be used in nonlinear optics for implementation of nonlinear processes . In this manner , the nonlinear response is significantly improved using coupling of electromagnetics modes of plasmonic metasurface with intersubband transitions of heterostructure . In this thesis , our goal is design of the plasmonic metasurface based on multi-quantum well substrate for third-harmonic generation process . Since , for these metasurfaces , the limitation factor is saturation effects for high input intensity , we modeled them . Then , we designed three multi-quantum wells and three resonators for third-harmonic generation process and finally their nonlinear response has been obtained and compared together .Keywords: Nonlinear Optics, Metasurface, Quantum Well, Third-Harmonic Generatio