Nowadays, due to compettetive and global markets, there exist more changabillity in design of products and life cycle of products has become too short. Therefore, in most industries, products are under alternation and this issue has direct influence on layout of facilities. Regarding that changes of demand increases costs of the organization because of adaptation; hence, organizations seek methods for satisfying demands with less costs. In this regard, recently, Dynamic Facility Layout Planning (DFLP) has been considred by many researchers. DFLP, based on prediction of changes that might occur in material flow in future, divides the future into time periods and yeilds an efficient layout by minimizing summation of material traortation and rearrangement costs. Plenty of factors are at work in proposing an efficient design for an industrial unit. In most studies, traortation cost of materials has been considered as the most significant criterion. But by considering the current competiveness and short life cycle merely enalyzing this criterion may not be appropriate. It is obvious, in different conditions those criteria should be considred which are acossiated with that condition. The effect of material flow intersection is of great importance in planning layout of facilities. In companies and industrial units because of various traortation vehicles, moving of personnel and performing operations of loading and unloading the intersection of material flow is increased. Moreover, space is a vital issue in both company and warehouse. Therefore, aisles are narrower since they restrict the production area. The intersection of material flow has been considered form both designing and operating perspectives. Although there have been many deveopments on layout planning problems, few studies has targeted intersections as a part of overall view to layout planning problem. Thus, in this research, initially material flow intersections are formulated then its effects on DFLP are investigated in order to design a better and more proper layout and also multi-objective dynamic facilities layout plannig model by cinsidering inetrsection of material flow is proposed.